Coinfection of HSV with other sexually transmitted diseases.

conditions (e.g., lupus and increased age) lead to antilipoidal antibodies and false positive results, hence a rapid, effective, practical confirmatory test is often required for diagnosis and treatment. Syphicheck is a one step rapid self performing test which can qualitatively detect presence of IgG and IgM class of treponema specific antibodies in serum or plasma within 15 minutes. It uses the principle of immunochromatography, a unique two site immunoassay on membrane. Positive results indicate a past or present infection, however a positive result should always be evaluated in correlation with clinical condition before arriving at final diagnosis. Manufacturers have reported 100% correlation between syphicheck and standard TPHA. Low levels of antibodies to Treponema pallidum at a very early primary stage of infection can give a negative result, nine such cases were detected in our study. However, Syphicheck in our study proved to be very helpful to exclude biological false positive results as well as to institute therapy in low titre (R1-R8) VDRL positive cases. As the results are available in 15 minutes and reproducible, it is better than standard TPHA which takes at least 3-4 hours.